According to GOSPEL: Filling in the GAP(DH) of NO-Mediated Neurotoxicity
نویسندگان
چکیده
In addition to its role in glycolysis, GAPDH has been implicated as a mediator of neurotoxicity triggered by nitrosative stress. In this issue of Neuron, Sen et al. identify a novel, negative regulator of this GAPDH neurotoxic pathway termed GOSPEL, which, like GAPDH itself, is regulated by S-nitrosylation.
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عنوان ژورنال:
- Neuron
دوره 63 شماره
صفحات -
تاریخ انتشار 2009